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Moxastine

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Chemical compound Pharmaceutical compound
Moxastine
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
  • none
Identifiers
IUPAC name
  • 2--N,N-dimethylethanamine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.020.626 Edit this at Wikidata
Chemical and physical data
FormulaC18H23NO
Molar mass269.388 g·mol
3D model (JSmol)
SMILES
  • CC(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN(C)C
InChI
  • InChI=1S/C18H23NO/c1-18(20-15-14-19(2)3,16-10-6-4-7-11-16)17-12-8-5-9-13-17/h4-13H,14-15H2,1-3H3
  • Key:BBIMHFSPNXQFAH-UHFFFAOYSA-N
  (what is this?)  (verify)

Moxastine (also known as mephenhydramine) is an antihistamine and anticholinergic.

It was developed in Czechoslovakia and sold in hydrochloride form as an antihistamine (Alfadryl).

It is, with 8-chlorotheophylline, a component of cocrystal/salt moxastine teoclate (mephenhydrinate) used as antiemetic (Theadryl; Kinedryl (with caffeine)).

References

  1. Saxena AK, Saxena M (1992). "Developments in antihistamines (H1)". In Jucker E (ed.). Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques. pp. 35–125. doi:10.1007/978-3-0348-7144-0_3. ISBN 978-3-0348-7146-4.
  2. Wardell WM (1978). Controlling the Use of Therapeutic Drugs An International Comparison. Washington, D.C: American Enterprise Institute for Public Policy Research. p. 242. ISBN 978-0-8447-3278-7.

See also

Acetylcholine receptor modulators
Muscarinic acetylcholine receptor modulators
mAChRsTooltip Muscarinic acetylcholine receptors
Agonists
Antagonists
Precursors
(and prodrugs)
See also
Receptor/signaling modulators
Nicotinic acetylcholine receptor modulators
Acetylcholine metabolism/transport modulators
Nicotinic acetylcholine receptor modulators
nAChRsTooltip Nicotinic acetylcholine receptors
Agonists
(and PAMsTooltip positive allosteric modulators)
Antagonists
(and NAMsTooltip negative allosteric modulators)
Precursors
(and prodrugs)
See also
Receptor/signaling modulators
Muscarinic acetylcholine receptor modulators
Acetylcholine metabolism/transport modulators
Histamine receptor modulators
H1
Agonists
Antagonists
H2
Agonists
Antagonists
H3
Agonists
Antagonists
H4
Agonists
Antagonists
See also
Receptor/signaling modulators
Monoamine metabolism modulators
Monoamine reuptake inhibitors


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