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Ensulizole

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Ensulizole
Skeletal formula
Space-filling model
Names
IUPAC name 2-Phenyl-3H-benzimidazole-5-sulfonic acid
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.044.078 Edit this at Wikidata
KEGG
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C13H10N2O3S/c16-19(17,18)10-6-7-11-12(8-10)15-13(14-11)9-4-2-1-3-5-9/h1-8H,(H,14,15)(H,16,17,18)Key: UVCJGUGAGLDPAA-UHFFFAOYSA-N
  • InChI=1/C13H10N2O3S/c16-19(17,18)10-6-7-11-12(8-10)15-13(14-11)9-4-2-1-3-5-9/h1-8H,(H,14,15)(H,16,17,18)Key: UVCJGUGAGLDPAA-UHFFFAOYAY
SMILES
  • O=S(=O)(O)c3ccc2c(c1ccccc1)nc2c3
Properties
Chemical formula C13H10N2O3S
Molar mass 274.29 g·mol
Hazards
Safety data sheet (SDS) Cole Parmer Material Safety Data Sheet
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒verify (what is  ?) Infobox references
Chemical compound

Ensulizole (INN; also known as phenylbenzimidazole sulfonic acid) is a common sunscreen agent. In 1999, the United States Food and Drug Administration regulated that the name ensulizole be used on sunscreen labels in the United States. Ensulizole is primarily a UVB protecting agent providing only minimal UVA protection. The scope of UVB is 290 to 340 nanometers whereas the UVA range is 320 to 400 nanometers. For better UVA protection, it must be paired with avobenzone, titanium dioxide, or zinc oxide; outside of the United States it can also be paired with a UV absorber of the Tinosorb or Mexoryl types. Because ensulizole is water-soluble, it has the characteristic of feeling lighter on skin. As such, it is often used in sunscreen lotions or moisturizers whose aesthetic goal is a non-greasy finish. The free acid is poorly soluble in water, so it is only used as its soluble salts.

References

  1. "International non-proprietary name". Medinet. Retrieved 6 May 2016.
  2. "Archived copy" (PDF). www.uspdqi.org. Archived from the original (PDF) on 14 December 2003. Retrieved 22 May 2022.{{cite web}}: CS1 maint: archived copy as title (link)
  3. eMedicine - Sunscreens and Photoprotection : Article by Stanley B Levy
  4. "Vibrant Science & Technology - EMD Group".

External links

Sunscreening agents approved by the US FDA or other agencies
  • UVA: 400–315 nm
  • UVB: 315–290 nm
  • Chemical agents unless otherwise noted
UVA filters
UVB filters
UVA+UVB filters
See also: Photoprotection, Sun protective clothing, Sun tanning, and Sunburn
Categories: