Enkephalinases are enzymes that degrade endogenous enkephalin opioid peptides. They include:
- Aminopeptidase N (APN)
- Neutral endopeptidase (NEP)
- Dipeptidyl peptidase 3 (DPP3)
- Carboxypeptidase A6 (CPA6)
- Leucyl/cystinyl aminopeptidase (LNPEP)
- Angiotensin-converting enzyme (ACE)
See also
References
- ^ Thanawala V, Kadam VJ, Ghosh R (October 2008). "Enkephalinase inhibitors: potential agents for the management of pain". Current Drug Targets. 9 (10): 887–94. doi:10.2174/138945008785909356. PMID 18855623. Archived from the original on 2013-04-14.
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: CS1 maint: unfit URL (link) - Lyons PJ, Callaway MB, Fricker LD (March 2008). "Characterization of carboxypeptidase A6, an extracellular matrix peptidase". The Journal of Biological Chemistry. 283 (11): 7054–63. doi:10.1074/jbc.M707680200. PMID 18178555.
- Benuck M, Berg MJ, Marks N (1982). "Separate metabolic pathways for Leu-enkephalin and Met-enkephalin-Arg(6)-Phe(7) degradation by rat striatal synaptosomal membranes". Neurochemistry International. 4 (5): 389–96. doi:10.1016/0197-0186(82)90081-X. PMID 20487892. S2CID 23138078.
Hydrolase: proteases (EC 3.4) | |||||||||||||||
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3.4.11-19: Exopeptidase |
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3.4.21-25: Endopeptidase | |||||||||||||||
3.4.99: Unknown |
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