Desaspidin - Misplaced Pages

Chemical compound Pharmaceutical compound

Desaspidin
Clinical data

ATC code	P02DX01 (WHO)
Identifiers
IUPAC name 2-Butanoyl-4--3,5-dihydroxy-6,6-dimethylcyclohexa-2,4-dien-1-one
CAS Number	114-43-2
PubChem CID	8238
ChemSpider	10295071
UNII	KV3495SGKS
KEGG	D07365
ChEMBL	ChEMBL2105606
CompTox Dashboard (EPA)	DTXSID00976317 DTXSID6074461, DTXSID00976317
ECHA InfoCard	100.003.680
Chemical and physical data
Formula	C₂₄H₃₀O₈
Molar mass	446.496 g·mol
3D model (JSmol)	Interactive image
SMILES CCCC(=O)C1=C(C(=C(C=C1O)OC)CC2=C(C(C(=C(C2=O)C(=O)CCC)O)(C)C)O)O
InChI InChI=1S/C24H30O8/c1-6-8-14(25)18-16(27)11-17(32-5)12(20(18)28)10-13-21(29)19(15(26)9-7-2)23(31)24(3,4)22(13)30/h11,27-28,30-31H,6-10H2,1-5H3 Key:GAHOBHHMYUYJDT-UHFFFAOYSA-N
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Desaspidin is an anthelmintic. Desapidin may occur in natural form within some plants such as Coastal woodfern, Dryopteris arguta. Since the 1950s the inhibition effects of desapidins upon phosphorylation in chloroplasts has been noted and studied.

References

Hogan CM (2008). Stromberg M (ed.). "Coastal Woodfern (Dryopteris arguta)". GlobalTwitcher. Archived from the original on 2011-07-11.
Bacon K (2001). Photosynthesis : photobiochemistry and photobiophysics. Dordrecht: Kluwer Academic Publishers. ISBN 0-7923-6791-X.

Binds tubulin	benzimidazole Triclabendazole
AChE inhibitor	phosphonic acid Metrifonate
Other/unknown	quinoline Arpraziquantel Praziquantel (+esafoxolaner/eprinomectin) Oxamniquine phenol Bithionol thiazole Niridazole thioxanthone Hycanthone Lucanthone antimony compounds Stibophen Tartar emetic

Binds tubulin	benzimidazole Albendazole
Other/unknown	quinoline Praziquantel (+esafoxolaner/eprinomectin) salicylanilide Niclosamide aminoacridine Quinacrine butyrophenone Desaspidin chlorophenol Dichlorophen

Binds tubulin	benzimidazole Mebendazole Albendazole Tiabendazole Fenbendazole Ciclobendazole Flubendazole
Glutamate-gated chloride channel, GABA receptor	avermectins Abamectin Doramectin Emamectin Eprinomectin (+esafoxolaner/praziquantel) Ivermectin Selamectin milbemycins Moxidectin (+fluralaner) Milbemycin oxime
NMDA	tetrahydropyrimidine Pyrantel pyrantel pamoate Oxantel Morantel Carbantel Febantel (aka felsantel)
Other/unknown	piperazine Piperazine Diethylcarbamazine thiazole Levamisole quinolinium Pyrvinium benzylammonium Bephenium naphthalenesulfonate Suramin Ascaridole Hexylresorcinol Santonin Tribendimidine Tetrachloroethylene

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