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Botiacrine

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Abandoned antiparkinsonian agent Pharmaceutical compound
Botiacrine
Clinical data
Other namesMo 876; DMA
Identifiers
IUPAC name
  • S- 9,9-dimethylacridine-10-carbothioate
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H24N2OS
Molar mass340.49 g·mol
3D model (JSmol)
SMILES
  • CC1(C2=CC=CC=C2N(C3=CC=CC=C31)C(=O)SCCN(C)C)C
InChI
  • InChI=1S/C20H24N2OS/c1-20(2)15-9-5-7-11-17(15)22(18-12-8-6-10-16(18)20)19(23)24-14-13-21(3)4/h5-12H,13-14H2,1-4H3
  • Key:QXRUCDDVUMKOPI-UHFFFAOYSA-N

Botiacrine (INNTooltip International Nonproprietary Name; developmental code name Mo 876) is a drug of the tricyclic family described as an antiparkinsonian agent which was either never marketed or was possibly marketed outside of the United States. It was first described in the literature by 1965. The drug is an acridine derivative and is structurally related to the tricyclic antidepressant dimetacrine.

References

  1. ^ Elks, J. (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 170. ISBN 978-1-4757-2085-3. Retrieved 20 October 2024.
  2. Negwer, M. (1994). Organic-chemical Drugs and Their Synonyms: (an International Survey). Akad.-Verlag. p. 1768. ISBN 978-3-05-500156-7. Retrieved 20 October 2024.
  3. Unlisted Drugs. Unlisted Drugs Committee of the Pharmaceutical Section, Science-Technology Group, Special Libraries Association. 1977. pp. 112–113. Retrieved 20 October 2024.
  4. "BOTIACRINE". Inxight Drugs. Retrieved 20 October 2024.
  5. Publishing, W.A.W.A. (2013). Pharmaceutical Manufacturing Encyclopedia. Volumes 1-4. William Andrew. pp. 657–658. ISBN 978-0-8155-1856-3. Retrieved 20 October 2024.
Antiparkinson agents (N04)
Dopaminergics
DA precursors
DA receptor agonists
MAO-B inhibitors
COMT inhibitors
AAAD inhibitors
Anticholinergics
Others
Tricyclics
Classes
Antidepressants
(Tricyclic antidepressants (TCAs))
Antihistamines
Antipsychotics
Anticonvulsants
Anticholinergics
Others


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