Arformoterol - Misplaced Pages

Chemical compound Pharmaceutical compound

Arformoterol
Clinical data


Trade names	Brovana
Other names	Arformoterol tartrate (USAN US)
AHFS/Drugs.com	Monograph
MedlinePlus	a602023
License data	US DailyMed: Arformoterol
Routes of administration	Inhalation
ATC code	None
Legal status
Legal status	US: ℞-only
Pharmacokinetic data
Protein binding	52–65%
Elimination half-life	26 hours
Identifiers
IUPAC name N-amino]ethyl] phenyl]formamide
CAS Number	67346-49-0
PubChem CID	3083544
IUPHAR/BPS	7479
DrugBank	DB01274
ChemSpider	2340731
UNII	F91H02EBWT
KEGG	D07463 D02981
ChEBI	CHEBI:408174
ChEMBL	ChEMBL1201137
CompTox Dashboard (EPA)	DTXSID1023077 DTXSID40110071, DTXSID1023077
Chemical and physical data
Formula	C₁₉H₂₄N₂O₄
Molar mass	344.411 g·mol
InChI InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)/t13-,19+/m1/s1 Key:BPZSYCZIITTYBL-YJYMSZOUSA-N
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Arformoterol, sold under the brand name Brovana among others, is a medication used for the treatment of chronic obstructive pulmonary disease (COPD).

It is a long-acting β₂ adrenoreceptor agonist (LABA) and it is the active (R,R)-(−)-enantiomer of formoterol. It was approved for medical use in the United States in October 2006. It is available as a generic medication.

Medical uses

Arformoterol is indicated for the maintenance treatment of bronchoconstriction in people with chronic obstructive pulmonary disease (COPD).

^ "Brovana- arformoterol tartrate solution". DailyMed. 13 May 2021. Retrieved 4 March 2022.
Loh CH, Donohue JF, Ohar JA (March 2015). "Review of drug safety and efficacy of arformoterol in chronic obstructive pulmonary disease". Expert Opinion on Drug Safety. 14 (3): 463–72. doi:10.1517/14740338.2015.998196. PMID 25563342. S2CID 7767810.
"Competitive Generic Therapy Approvals". U.S. Food and Drug Administration (FDA). 29 June 2023. Archived from the original on 29 June 2023. Retrieved 29 June 2023.

"Arformoterol". Drug Information Portal. U.S. National Library of Medicine.
"Arformoterol tartrate". Drug Information Portal. U.S. National Library of Medicine.

Short-acting β₂ agonists	Bitolterol Carbuterol Fenoterol Isoetarine Pirbuterol Procaterol Reproterol Rimiterol Salbutamol (albuterol)/Levosalbutamol (levalbuterol) Terbutaline Tulobuterol
Long-acting β₂ agonists	Bambuterol Clenbuterol Formoterol/Arformoterol Salmeterol
Ultra-long-acting β₂ agonists	Abediterol Carmoterol Indacaterol Olodaterol Vilanterol
Other	Clorprenaline Ephedrine (+theophylline, +theophylline/phenobarbital, theophylline/hydroxyzine) Epinephrine Etafedrine Hexoprenaline Isoprenaline (isoproterenol) Methylephedrine Orciprenaline (metaproterenol) Racephedrine

Eicosanoid inhibition

Leukotriene antagonists	Montelukast Pranlukast Zafirlukast
Arachidonate 5-lipoxygenase inhibitors	Zileuton
Thromboxane receptor antagonists	Ramatroban Seratrodast
Non-xanthine PDE4 inhibitors	Ibudilast Roflumilast