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Alseroxylon

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Pharmaceutical drug Pharmaceutical compound
Alseroxylon
Reserpine, the major component of alseroxylon
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Alseroxylon (Rautensin, Rauwiloid) is a norepinephrine reuptake inhibitor that has been investigated in the treatment of hypertension and angina pectoris and as a sedative in psychoses. It was at one time approved for use in the United States, but has since been discontinued.

Alseroxylon is a purified fat-soluble extract of the root of Rauvolfia serpentina, containing reserpine and other nonadrenolytic amorphous alkaloids.

References

  1. Green RS, Davolos D (May 1956). "A long-term study of the effect of crude Rauwolfia serpentina and of its alseroxylon fraction in patients with hypertension". The American Journal of Medicine. 20 (5): 760–73. doi:10.1016/0002-9343(56)90158-9. PMID 13313574.
  2. ^ DrugBank DB00386
  3. Approved Drug Products with Therapeutic Equivalence Evaluations (33rd ed.). 2013. {{cite book}}: |work= ignored (help)
Monoamine reuptake inhibitors
DATTooltip Dopamine transporter
(DRIsTooltip Dopamine reuptake inhibitors)
NETTooltip Norepinephrine transporter
(NRIsTooltip Norepinephrine reuptake inhibitors)
SERTTooltip Serotonin transporter
(SRIsTooltip Serotonin reuptake inhibitors)
VMATsTooltip Vesicular monoamine transporters
Others
See also: Receptor/signaling modulatorsMonoamine releasing agentsAdrenergicsDopaminergicsSerotonergicsMonoamine metabolism modulatorsMonoamine neurotoxins
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