Aga Khan may refer to:
- Aga Khan, the hereditary title of the Imam (spiritual and general leader) of the Ismaili Nizārī Muslims
- Aga Khan I (1804–1881), the first Aga Khan, and 46th Imam
- Aga Khan II (1830–1885), the second Aga Khan and 47th Imam
- Aga Khan III (1877–1957), the third Aga Khan and 48th Imam
- Aga Khan IV (b. 1936), the fourth and current Aga Khan and 49th Imam
Other people
- Prince Sadruddin Aga Khan (1933–2003), United Nations High Commissioner for Refugees from 1966 to 1978
- Yasmin Aga Khan (b. 1949), American philanthropist known for raising public awareness in Alzheimer's disease
Other
- Aga Khan case, an 1866 court case in India regarding the authority of the Aga Khan
- Aga Khan Palace in Pune, India
- Aga Khan Development Network, whose subsidiaries include:
- Aga Khan Foundation (AKF)
- Aga Khan Health Services (AKHS)
- Aga Khan Hospital (disambiguation), any of eight medical institutions around the world, run by AKHS
- Aga Khan Agency for Microfinance (AKAM)
- The Aga Khan School, Dhaka
- Aga Khan Fund for Economic Development (AKFED)
- Aga Khan Planning and Building Services (AKPBS)
- Focus Humanitarian Assistance (FOCUS)
- Aga Khan Education Services (AKES)
- Aga Khan Trust for Culture (AKTC)
- Aga Khan Award for Architecture (AKAA), an architectural award established by the Aga Khan in 1977
- University of Central Asia (UCA)
- Aga Khan University (AKU), Pakistan's first private, autonomous university
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