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Afurolol

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Chemical compound Pharmaceutical compound
Afurolol
Clinical data
ATC code
  • none
Identifiers
IUPAC name
  • 7--3H-isobenzofuran-1-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H21NO4
Molar mass279.336 g·mol
3D model (JSmol)
SMILES
  • O=C1OCc2cccc(OCC(O)CNC(C)(C)C)c12
InChI
  • InChI=1S/C15H21NO4/c1-15(2,3)16-7-11(17)9-19-12-6-4-5-10-8-20-14(18)13(10)12/h4-6,11,16-17H,7-9H2,1-3H3
  • Key:NFXPPCYKSAAUMQ-UHFFFAOYSA-N
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Alfurolol is a beta blocker.

References

  1. "The Use of Common Stems in the Selection of International Nonproprietary Names (INN) for Pharmaceutical Substances: Alphabetical list of stems together with corresponding INNs". Archived from the original on March 7, 2012.
  2. Narimatsu S, Takemi C, Kuramoto S, Tsuzuki D, Hichiya H, Tamagake K, Yamamoto S (May 2003). "Stereoselectivity in the oxidation of bufuralol, a chiral substrate, by human cytochrome P450s". Chirality. 15 (4): 333–9. doi:10.1002/chir.10212. PMID 12666241.
Sympatholytic (and closely related) antihypertensives (C02)
Sympatholytics
(antagonize α-adrenergic
vasoconstriction)
Central
α2-Adrenergic receptor agonists
Adrenergic release inhibitors
Imidazoline receptor agonists
Ganglion-blocking/nicotinic antagonists
Peripheral
Indirect
Monoamine oxidase inhibitors
VMAT inhibitors
Tyrosine hydroxylase inhibitors
Direct
α1-Adrenergic receptor blockers
Non-selective α-adrenergic receptor blockers
Other antagonists
Serotonin receptor antagonists
Endothelin receptor antagonists (for PHTooltip Pulmonary hypertension)
Adrenergic receptor modulators
α1
Agonists
Antagonists
α2
Agonists
Antagonists
β
Agonists
Antagonists


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